Saint-Estèphe (French pronunciation: [sɛ̃.t‿ɛstɛf]; Gascon: Sent Estèfe) is a commune in the Gironde department in Nouvelle-Aquitaine in southwestern France.

The area is separated from Château Lafite-Rothschild in Pauillac to the south by the Jalle de Breuil stream and its vineyards cover around 12 km2 (4.6 sq mi) on the banks of the Gironde estuary.

To the south-east corner of the appellation area, they are similar to those of Pauillac, with deep gravels lying on a hard sandstone base.

In parts, veins of alios (a reduced form of iron) can be found.

[3] The layers of gravel on top of clay lead to comparatively poor drainage, and the harvest is one of the latest of the whole region, although this water retention can be of use in vintages of low rainfall.