Saint-Front-sur-Nizonne (French pronunciation: [sɛ̃ fʁɔ̃ syʁ nizɔn], literally Saint-Front on Nizonne; Occitan: Sent Front de Champs Niers) is a commune in the Dordogne department in Nouvelle-Aquitaine in southwestern France.

In 1912, the commune of Saint-Front-de-Champniers changed its name to Saint-Front-sur-Nizonne.

The Lizonne, also called Nizonne, flows west through the middle of the commune.

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