Saint-Girons (French pronunciation: [sɛ̃ ʒiʁɔ̃] ⓘ; Languedocien: Sent Gironç) is a commune in the Ariège department in southwestern France.

Unlike its close neighbour Saint-Lizier, Saint-Girons isn't an ancient city; there was however a lucus on its present territory where some Roman finds were made during the construction of the train station in the beginning of the twentieth century.

In the ninth century some of his relics were supposedly buried in Saint Girons' Church, around which the city later developed.

Saint-Girons has a moderate but warm oceanic climate, that is quite prone to temporary vast extremes in temperature as a result of its inland position.

Stage 8 of the 2009 Tour de France finished in Saint-Girons, after travelling 176 km from Andorra la Vella.