Saint-Grégoire (French pronunciation: [sɛ̃ ɡʁeɡwaʁ]; Breton: Sant-Gregor; Gallo: Saent-Gregoèrr) is a commune in the department of Ille-et-Vilaine, Brittany, northwestern France.

Inhabitants of Saint-Grégoire are called grégoriens in French.

The city hosts offices of important firms such as KPMG, or the "Banque Populaire Grand Ouest" and others well-known firms that make the commune important regarding the other communes around.

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