Saint-Isidore (French pronunciation: [sɛ̃t‿izidɔʁ]) is a municipality in La Nouvelle-Beauce Regional County Municipality in the Chaudière-Appalaches region of Quebec, Canada.

Its population was 3,286 as of the Canada 2021 Census.

Founded in 1855, it is named after Isidore of Seville.

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