Saint-Léger-du-Ventoux (French pronunciation: [sɛ̃ leʒe dy vɑ̃tu]; Occitan: Sant Laugier d'Aurenja;[a] Provençal dialect: Sant Laugier dau Ventor, before 1953: Saint-Léger-d'Orange[3]) is a rural commune in the Vaucluse department in the Provence-Alpes-Côte d'Azur region in Southeastern France.

In 2021, it had a population of 29.

It is located on the departmental border with Drôme, which is also the regional border with Auvergne-Rhône-Alpes.

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