Saint-Martin-lès-Seyne (French pronunciation: [sɛ̃ maʁtɛ̃ lɛ sɛn], literally Saint-Martin near Seyne; Vivaro-Alpine: Sant Martin de Sèina) is a commune in the Alpes-de-Haute-Provence department in southeastern France.

With 13 inhabitants (as of 2019), it is the second least populated commune in the department, after Majastres.

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