Saint-Ouen-sur-Loire (French pronunciation: [sɛ̃.t‿wɛ̃ syʁ lwaʁ], literally Saint-Ouen on Loire) is a commune in the Nièvre department in central France.

[3] In 2021, the town had 507 inhabitants.

The commune's landmarks include a neo-gothical church from the early 20th century.

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