Saint-Pierre (/ˌseɪnt piˈɛər/, /ˌsæ̃-/; French pronunciation: [sɛ̃ pjɛʁ] ⓘ; Martinican Creole: Senpiè) is a town and commune of France's Caribbean overseas department of Martinique, founded in 1635 by Pierre Belain d'Esnambuc.

Before the total destruction of Saint-Pierre by a volcanic eruption in 1902, it was the most important city of Martinique culturally and economically, being known as "the Paris of the Caribbean".

The Great Hurricane of 1780 produced a storm-surge of 8 metres (25 ft) which "inundated the city, destroying all houses" and killed 9,000 people.

The entire population of the town, as well as people from neighboring villages who had taken refuge in the supposedly safe city, died, except for three people—a young girl, Havivra da Ifrile, a prisoner by the name of Louis-Auguste Cyparis (known also by various other names), who later toured the world with the Barnum and Bailey Circus, and Léon Compère-Léandre, who lived at the edge of the city.

Actually, there was considerable eruptive activity in the two weeks prior to the fatal blast, but since the phenomenon of the pyroclastic flow (French: nuée ardente) was not yet understood, the danger was perceived to be from lava flows, which, it was believed, would be stopped by two valleys between the volcano and the city.