Saint-Pierre-d'Argençon (French pronunciation: [sɛ̃ pjɛʁ daʁʒɑ̃sɔ̃]; Vivaro-Alpine: Sant Peire d'Argençon) is a commune in the Hautes-Alpes department in the Provence-Alpes-Côte d'Azur region in Southeastern France.

It is located on the departmental border with Drôme, which is also the regional border with Auvergne-Rhône-Alpes.

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