Saint-Rambert-en-Bugey (French pronunciation: [sɛ̃ ʁɑ̃'bɛʁ ɑ̃ by'ʒɛ] ⓘ, literally Saint-Rambert in Bugey) is a commune in the Ain department in eastern France.

The commune takes its name from St Rambert (or Ragnebert) who was assassinated here in the 7th century.

The site soon became popular for pilgrimage and an influential abbey was built in the town.

Saint-Rambert-en-Bugey station has rail connections to Lyon, Ambérieu-en-Bugey and Chambéry.

The average annual rainfall is 1,512.4 mm (59.54 in) with November as the wettest month.