Saint-Romain (French pronunciation: [sɛ̃ ʁɔmɛ̃]) is a commune in the Charente department in southwestern France.

In terms on surface area, Saint-Romain is the largest commune of its canton, spreading up to 200m of Aubeterre town center.

The commune sits on a low Cretaceous limestone plateau.

No rivers traverse Saint-Romain, but two small tributaries have their sources there: the Beauronne which flows south-west into the Dronne river and a tributary of the Tude in the north, as well as the Écrevansou, a small spring that follows the commune's eastern limits.

In 1789, on the eve of the French Revolution, Saint-Romain, like many parishes, issued a list of grievances.