Saint-Sébastien (French pronunciation: [sɛ̃ sebastjɛ̃]) is a municipality in Le Granit Regional County Municipality in the Estrie region of Quebec, Canada.

It is named after Saint Sebastian, who died c. 288.

In the 2021 Census of Population conducted by Statistics Canada, Saint-Sébastien had a population of 674 living in 301 of its 329 total private dwellings, a change of 2.6% from its 2016 population of 657.

[4] The politician Madeleine Bélanger and the novelist Andrée A. Michaud were born in Saint-Sébastien.

This Quebec location article is a stub.