Saint-Samson-sur-Rance (French pronunciation: [sɛ̃ sɑ̃sɔ̃ syʁ ʁɑ̃s], literally Saint-Samson on Rance; Breton: Sant-Samzun) is a commune in the Côtes-d'Armor department of Brittany in northwestern France.

Inhabitants of Saint-Samson-sur-Rance are called samsonnais in French.

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