Saint-Saturnin-lès-Avignon (French pronunciation: [sɛ̃ satyʁnɛ̃ lɛ.z‿aviɲɔ̃], lit.

"St Saturnin near Avignon"; Provençal Occitan: Sant Savornin d'Avinhon) is a commune in Greater Avignon in the Vaucluse department in the Provence-Alpes-Côte d'Azur region in Southeastern France.

In 2021, it had a population of 5,119.

The poet Jean Tortel (1904–1993) was born in Saint-Saturnin-lès-Avignon.

To differentiate the commune's inhabitants from those of Saint-Saturnin-lès-Apt to the east, the first are called Saint-Saturninois (masculine) and Saint-Saturninoises (feminine) in French, whereas the latter are called Saturninois (masculine) and Saturninoises (feminine).