Saint-Sulpice (French pronunciation: [sɛ̃ sylpis] ⓘ) is a commune in the Haute-Saône department in the region of Bourgogne-Franche-Comté in eastern France.

As of 2023, Saint-Sulpice reported a total of 127 inhabitants with a population density of 36.0 people/km2 (93 people/sq mi).

Saint-Sulpice sits close to five major cities; Strasbourg 148 km (closest), Lyon 236 km, Paris 334 km, Nice 436 km & Marseilles 483 km.

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