Saint-Thomas-Didyme (French pronunciation: [sɛ̃ tɔma didim]) is a municipality in Maria-Chapdelaine Regional County Municipality in the Saguenay–Lac-Saint-Jean region of Quebec, Canada.

It had a population of 703 in the Canada 2021 Census.

Population trend:[4] Private dwellings occupied by usual residents: 364 (total dwellings: 518) Mother tongue:[5]

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