Moving into a one-room schoolhouse that same year, Miss Flora Shafer taught the first class of 15 students.

By 1905, students were receiving their instruction from the Sisters of Divine Providence in the same building, which by 1912 had been expanded from one room to three floors.

[2] With an average enrollment of 80 students per grade level during the 1970s, facilities were once again expanded during that decade with Rita Adams, CDP serving as the school's principal until 1990.

A scholarship program exists, as do on-site morning and after-school extended care services.

[5] Activities offered at Saint Anne School include PA Junior Academy of Science, Student Newspaper, Forensics, English Festival, AV Club, Lectors, Altar Servers and Lectors, Children's Choir, Spelling Bee, and Band & Advanced Band.