Saint Joseph, affectionately called St. Joe County by locals, is an unincorporated community in German Township, Vanderburgh County, Indiana, United States and centered on St. Joseph Catholic Church.

[2] Along with that of Darmstadt, its colonization marked the beginning of German-American immigration to southern Indiana.

The church is named for the Saint Joseph the Carpenter, the father of Jesus.

Unlike most other local communities, St. Joseph has never had a railway station.

[4] The nickname "St. Joe County" originates from the fact that there are multiple churches by the name of St. Joseph in the Roman Catholic Diocese of Evansville and Vincennes, and different names were needed to distinguish one from the next in conversation and on paperwork.