The first year Saint Kitts and Nevis participated in the Olympics, they sent ten athletes, the most the country has ever sent.

[3][4][5] Saint Kitts and Nevis only sent one male and one female athlete to the 2000 Summer Olympics, who both performed well.

Kim Collins competed in two events, and was the only athlete from Saint Kitts and Nevis to advance to the finals.

One athlete, the sprinter Tameka Williams, admitted prior to competing in the London Games that she took Blast Off Red, which is typically used to increase the performance of horses and greyhounds.

[16] The 4 × 100 meter relay team, made up of—Antoine Adams, Delwayne Delaney, Brijesh Lawrence, Jason Rogers, and Lestrod Roland—set a national record for Saint Kitts and Nevis with a time of 38.41 seconds.

[17] Saint Kitts and Nevis had seven participants at the 2016 Summer Olympics, led by team captain Antoine Adams.

[18] At 40 years old, Kim Collins was the first 40-year old to run a sub 10 second 100-meter dash, for his fifth consecutive Olympic Games.

[19] Collins advanced the furthest of any Saint Kitts and Nevis athlete, reaching the semifinals of the 100 meter dash.

[25] Troy Nisbett became the first swimmer to represent Saint Kitts and Nevis at the Olympics,[26] and the youngest ever Olympian from the country.