The monks of the Abbey live their faith according to the Benedictine discipline of 'prayer and work', praying the Divine Office five times daily, celebrating daily Masses in English and Latin, and working in the two parishes under their pastoral care and in the Saint Louis Priory School, which the Abbey runs as an apostolate.

[1][2][3] The Abbey and its school sit on a 150-acre (0.61 km2) campus in west St. Louis County, in the city of Creve Coeur.

They came at the invitation of Cardinal Joseph E. Ritter and a group of prominent St. Louis lay Catholics, who desired a boys' school in their community run according to the English Benedictine educational tradition.

Timothy Horner, arrived in St. Louis in the summer of 1955 and set about the formation of a new monastic community, with Fr.

[16] In addition to their other duties and ministries, many of the brothers are directly involved in the Abbey's school, teaching classes in most areas of instruction including Theology, Latin, Fine Arts, English, Mathematics, and Science, and coaching sporting teams including Tennis and Rugby.

[17] In line with the Benedictine tradition of offering hospitality and respite to travelers, the Abbey maintains a guest wing on the south side of the monastery with five rooms and two gardens.

The church also contains a 14th-century sculpture of the Madonna and Christ child, a 17th-century holy font in the Della Robbia style, and more modern sacred art by artists from the United States, Great Britain, Spain, and France.