Saint Luke's North Hospital–Smithville Campus is located at 601 South 169 Highway in Smithville, Missouri.

It is the Northland area's first hospital and is a 92-bed facility.

Arch E. Spelman founded Smithville's first hospital in 1938 in the old downtown, as an 11-bed space.

The hospital includes Saint Luke's Primary Care–Smithville, a family medicine clinic, an inpatient rehabilitation unit, and an inpatient mental health unit.

This article relating to a hospital in Missouri is a stub.