Saint Mark Preaching in Alexandria is an oil painting by the Italian Renaissance artists Gentile and Giovanni Bellini, dated to 1504–1507 and held in the Pinacoteca di Brera, in Milan.

The cycle of paintings with stories of the life of Saint Mark was completed around 60 years later by Giorgione and Tintoretto, and is today housed in the Pinacoteca di Brera and the Accademia in Venice.

This painting combines two distinct moments in time, one ancient and one contemporary to Bellini's life, as well as three different places, Alexandria, Venice, and a mountainous landscape in the background.

The Scuola Grande di San Marco was reconstructed after a massive fire took a hit on the old structure on 31 March 1485 toward the end of the fifteenth century.

The large-scale oil painting depicts a massive stage in the center of the main city and the pavement appears to be created of large square red brick stones.

Behind the stage are three tall blue domed temples along with minaret-like towers and big square light colored houses, along the side as well.

The men are shown wearing caftans, frocks, cloaks, turbans, and immense hats, while the women are dressed in white from head to ankle-length veils.

The attribution of the different pieces of the work to every artisan is as yet a matter of discussion among researchers; in any case, the most generally held view allots Gentile the meaning of the primary lines of the scene, where components of Venetian engineering are superimposed on structures of unmistakably Mediterranean and Oriental inference.

With its structure of round curves, its marble-shaded façade adornments, and glossy vault covers, it reviews a portion of the primary qualities of early Byzantine holy places.

[3] The most generally held view allots Gentile the meaning of the primary lines of the scene, where components of Venetian engineering are superimposed on structures of unmistakably Mediterranean and Oriental inference.

[5] Gentile was an equipped and fastidious painter and ran the Bellini family workshop, yet he was eclipsed by his more skilled and imaginative sibling Giovanni.