Sainte-Foy-la-Grande (French pronunciation: [sɛ̃t fwa la ɡʁɑ̃d]; Occitan: Senta Fe la Granda) is a commune in the Gironde department in Nouvelle-Aquitaine in southwestern France.

The town was founded in 1076, near a priory where Sainte Foy was worshipped.

A lot of the town is made from medieval buildings which date back to the 15th century.

During the French reformation in the 16th century, Sainte-Foy became a centre of Calvinism, known as "Little Geneva"; held by the Huguenots during the French Wars of Religion, the town was fought over by both sides.

Even after Protestant worship was banned by the 1685 Edict of Fontainebleau, the faith continued to be practised in secret, and in 1828, it became the location of one of the first Protestant schools established in France since 1685.