Sainte-Jamme-sur-Sarthe (French pronunciation: [sɛ̃t ʒam syʁ saʁt], literally Sainte-Jamme on Sarthe) is a commune in the Sarthe department in the region of Pays de la Loire in north-western France.

The area was host to a knighting tournament attended by William Marshal, 1st Earl Pembroke, in 1166.

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