Santi Cosma e Damiano (or Santa Chiara) is a Roman Catholic church in Alcamo, in the province of Trapani, Sicily, southern Italy.

[1] The church has one nave and presents a tambour which inside repeats the shape of the main body with a hexagonal plan, while the chapels are delimited by some pillars in Corinthian style.

Thanks to its restyling probably inspired by the Roman church of Saint Ives alla Sapienza by the architect Francesco Borromini,[2] it became in 1725 an example of the most beautiful Sicilian baroque.

The Clares of this convent, besides taking part in the religious rites in the Church with their chants, have helped in the birth and revival of other nunneries in Sicily and Sardinia.

Nowadays they make silk holy paraments, embroidered with gold and silver threads, or embellished with gems and pieces of coral; they also prepare hosts for several churches.