The series is the sequel of Saiyuki Reload, premiered on TV Tokyo from April 1, 2004 to September 23, 2004 and consist of 26 episodes.

Saiyuki Reload Gunlock was licensed by Geneon in North America,[3] A total of seven DVDs of the Saiyuki Reload Gunlock anime series were released by Geneon, along with an Artbox DVD which was published on May 2, 2006.

[4][5] A Complete box set was originally solicited for November 20, 2007, but never released due to Geneon cancelling DVD sales.

[9][10] On September 27, 2022, Discotek Media licensed the anime for a Blu-ray release in standard definition.

[16] Also, a new anime series produced by Liden Films titled Saiyuki Reload: Zeroin has been announced on January 10, 2021.