In 2006 the club reached its first final in the Primera A only to lose it to Puebla FC in a Penalty shoot out.

In 2013 the team returned as Salamanca F.C., after spending several years in the Third Division of Mexico without winning promotion, on July 3, 2019 the team attempted to participate in the Liga Premier de México (Second Division) – Serie B, this after reaching an agreement with the Real Potosino's management, after the agreement, the team from San Luis Potosí had to move to Salamanca and be rebranded as Salamanca F.C.

[6] This team was dissolved at the end of the 2022–23 season due to the impossibility of competing with the new project that has arrived in the city.

[7] The relocation of the club occurred after a merger with Petroleros de Salamanca, because the local oil sector was interested in having a professional team in the city, for this reason the team was unofficially called Catedráticos Petroleros.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.