Salem is a city in Harrison County, West Virginia, United States.

Notable settler family names included Lippincott, Maxson, Babcock, Plumer, Davis, and Fitz-Randolph.

New Salem was formally chartered and made a town by legislative enactment of the Virginia Assembly on December 19, 1794, on land owned by Samuel Fitz Randolph.

As late as 1870, Charles A. Burdick came to town as a Seventh Day Baptist missionary, feeling the need for an educational institution in the area, opened a school, though it operated for only two semesters.

The more recent fire burned the old city bank building, several store fronts, and several residences; five structures in all were damaged.

[8] The Salem College Administration Building was completed in 1910 and listed on the National Register of Historic Places in 1989.

The Salem College Administration building was later torn down in early 2024 due to it being condemned for many years.