[1] Salma Kikwete originally worked as a teacher for more than twenty years.

[1] In 2005, the government launched a national campaign for voluntary HIV/AIDS testing in Dar es Salaam.

[2] As of 2009, she was Vice President of the Eastern Region of the Organisation of African First Ladies against HIV/AIDS (OAFLA).

[1] In 2012, the First Lady Salma Kikwete, former Botswana President Festus Mogae and ten other African figures partnered with UNESCO and UNAIDS to support the Eastern and Southern Africa Commitment on HIV Prevention and Sexual Health for Young People, which was launched in November 2011.

[1] Over a year after her husband left office, Salma Kikwete was appointed to a seat in the National Assembly by President John Magufuli on 1 March 2017.