Saltos del Guairá (Spanish pronunciation: [ˈsalto ðel ɣwajˈɾa]) is a city in Paraguay.

The Colony Salto del Guairá, was founded on March 3 of 1959, by a private company called "Colonizadora Salto del Guairá S.A" according to a note received by the firm's directory, formed by Mr. José Luís Serrati, Mr. Ibrahin Abud and Mr. Carlos Ricardo Méndez Goncalvez.

This depended of Hernandarias District, and, at that time it was integrated by three renowned neighbors: Col (SR.) Isabelino Pimienta Medina (+) as the president, Carmelo Peralta as the treasurer, and for the secretary position, Prof. Pedro Ramón Girett.

The Municipal board requested to be elevated to first category on May 29 of 1974, based on the legal dispositions and for having the requirements demanded.

In consequence by Decree Law 7131 dated July 2 that year, it promoted to the First Class City of Salto del Guairá, becoming capital of Canindeyú Department.

Its establishment coincides with the period of advancing agricultural frontier eastward, the construction of the Itaipu Dam and the extinction of the waterfalls in Saltos del Guairá Salto del Guairá is in the Department of Canindeyú, the eastern of the country, its geographical location is latitude 24 º 04 'S and longitude 54 ° 20 W. This makes District boundaries to the north with the cities of Novo Mundo (MS) and Guaira (PR), Brazil as the latter taking the limit Paraná River and east, separated from this country in the mountains Amambay and Mbarakayú and the Paraná River, respectively.

To the south the river divides the Itambey Department of Alto Paraná and the mountains of San Joaquin Caaguazú.

The city of Salto del Guairá, as a pole of development in the north of the country has an interesting infrastructure, as it is endowed with public buildings, government, military establishments, public and private hospitals, places of sport and recreation, commercial premises, schools, colleges, universities and religious temples.

The Paraná River and the Itaipu Lake, with its strong potential waterway, have a reduced impact, becoming international channels of communication with Brazilian surrounding populations, such as the Mundo Novo and Guaira, with which there is a rafts system connection.