Saluda Factory Historic District is a national historic district located at West Columbia, Lexington County, South Carolina.

The Saluda Factory ruins consist of the granite foundation and sluices from a textile mill that operated on the river between the years 1834 and 1884.

It held 1,300 Union soldiers, who were confined there from the autumn of 1864 to February 1865, and subsequently transferred to Charlotte, North Carolina.

The old State Road, originally the Cherokee Path, bounded Saluda Factory and Camp Sorghum on the east.

This article about a property in Lexington County, South Carolina on the National Register of Historic Places is a stub.