Pietro Salvatore Colombo, OFM (28 October 1922 – 9 July 1989) was an Italian Catholic prelate who served as Bishop of Mogadiscio from 1976 until his assassination in 1989.

He served the people of Somalia from 1946, after he had been ordained a priest in Milan, Italy.

The government of President Siad Barre did not tolerate proselytizing, but was comfortable with the humanitarian aid dispensed by the Church.

Four days after Colombo's death, several Somali sheikhs and other men were arrested on suspicion of having a connection to the assassination.

Currently, the welfare of Catholics in Somalia is overseen by the Apostolic Administrator of Mogadishu, Giorgio Bertin, OFM, the Bishop of Djibouti.