Salvatore Pennacchio (born 7 September 1952 in Marano, Italy) is a Catholic archbishop and diplomat of the Holy See, currently president of the Pontifical Ecclesiastical Academy.

He attended the Pontifical Ecclesiastical Academy and entered the diplomatic service of the Holy See.

On 28 November 1998 he was appointed by Pope John Paul II as the apostolic nuncio to Rwanda and titular archbishop of Montemarano.

He received episcopal consecration on 6 January 1999 by Pope John Paul II, co-consecrated by Giovanni Battista Re and Francis Monterisi.

[1] On 8 May 2010, Pope Benedict XVI appointed him Apostolic Nuncio to India[2] and on 13 November 2010 to Nepal.