Between 1980 and 1983 he founded a chain of computerized information kiosks in Tel Aviv, and in 1982 worked for the Nessim D. Gaon Group in Geneva, Paris, and New York City.

[7] In Israel, in 1995, he was found guilty on three counts of securities fraud along with two other men, Nissim Avioz and Dov Landau.

According to Vaknin: "I was borderline, schizoid, but the most dominant was NPD," and on this occasion he accepted the diagnosis, because, he wrote, "it was a relief to know what I had.

He writes regularly for other publications, such as the International Analyst Network,[16] Brussels Morning,[17] and the online American Chronicle.

[18] Vaknin was a visiting professor at Southern Federal University in Rostov Oblast, Russia in 2017–22[19] holding a course of lectures there on personality theory.

[22] Vaknin served as a founding member of the Steering Committee for the Advancement of Healthcare in the Republic of North Macedonia between 2009-2011.

The postulated particle (chronon) is not only an ideal clock, but also mediates time itself (analogous to the relationship between the Higgs boson and mass).

[6][29] In his view, narcissists have lost their "true self", the core of their personality, which has been replaced by delusions of grandeur, a "false self".

[35] Vaknin suggests that narcissists and their intimate partners regard each other as introjected, idealized maternal figures ("snapshotting"[36]) in a shared fantasy and attempt to re-enact early childhood dynamics in their relationships, in what he dubs a "dual mothership".

[38] He believes that disproportionate numbers of pathological narcissists are at work in the most influential reaches of society, such as medicine, finance and politics[10] as a manifestation of growing collective narcissism.

[40] It is based on recasting pathological narcissism as a form of CPTSD (Complex Post-traumatic Stress Disorder) and arrested development, which result in an addictive personality with a dysfunctional attachment style.

[46] In 2019, Vaknin appeared in the online documentary Plugged-in: The True Toxicity of Social Media Revealed produced by Richard Grannon.