[3][4][5][6] Quek started playing hockey whilst at Birkenhead High School, and attended trials for the Wirral under-12 team.

[8][3] In 2005, Quek was part of the England team that won the Girl's (Under-18s) Four Nations Invitational Tournament by defeating Holland on penalties after a 1–1 draw in the final.

[8] She was not selected for the Great Britain squad for the London 2012 Olympic Games,[3] but did play for England at the 2013 Women's EuroHockey Nations Championship,[8] at the 2014 Women's Hockey World Cup (where the England team finished eleventh of twelve, their worst-ever placing),[13] and at the 2014 Commonwealth Games where the team won silver.

[20] The team defeated the Netherlands on penalties after a 3–3 draw, winning the first women's hockey gold medal in the Olympics for Great Britain.

[22] In September 2016, a group of Russian hackers calling themselves "Fancy Bears" hacked into the WADA database and revealed that Quek, along with many of her fellow Team GB members, had been granted a Therapeutic Use Exemption (TUE) for various medical prescriptions.

She revealed in an interview with The Guardian that she had to make the choice at the age of 16 between pursuing a professional career in hockey or football, as splitting her time between the two sports was hindering her progress in both.

[24] On 23 March 2018, Quek was selected to play in an All-Stars team versus FA People's Cup challengers in a 12-hour fundraising match for Sport Relief.

[15] In 2017, she became a sports columnist for the Metro newspaper,[36] and in 2018 wrote a piece for the BBC about the challenges that women face in the media's portrayal of female athletes on and off the field.

[38] In August 2019, she began hosting the BBC's flagship football phone-in programme, 606, with regular pundit Robbie Savage.

Her appointment was part of a change to the programme's line-up that saw Paddy McGuinness take over as host and Quek become the show's first permanent female captain alongside former rugby union player Ugo Monye.

and won £16,000 for WellChild, which made her the most successful contestant of the Celebrity Special edition, which also featured Harry Redknapp and Craig Charles.

In June 2024, Quek released a children's nonfiction book, Roar: A celebration of Great Sporting Women, published by Allen & Unwin.

[45] Quek is married to Tom Mairs, a property entrepreneur who appeared as the titular "Secret Millionaire" on the reality show of the same name in 2010.

[52] On 11 October 2021, Quek announced she was pregnant with her second child[53] and gave birth in March 2022 to a son, Isaac Gregory Mairs.