[2][3] Ishaq made his professional debut in 2004–05 Pakistan Premier League with Panther Club of his hometown Faisalabad, finishing the season in relegation zone at 11th position with 30 points, but avoided relegation due to Allied Bank who had finished in 8th position dissolving their team at the end of the season.

Ishaq was a regular in the starting eleven throughout the season as Khan Research Laboratories finished 3rd, conceding only 12 goals in 20 games.

[8] The 2008–09 season saw Ishaq winning his first silverware, as Khan Research Laboratories won the 2009 National Football Challenge Cup, defeating Pakistan Airlines 1–0 in the finals, thanks to a 64th-minute goal by Muhammad Qasim.

[10] On 4 October 2009, Ishaq scored the lone goal in the 90+1 minute as Khan Research Laboratories defeated Pak Elektron 1–0.

He won the league as Khan Research Laboratories finished at the top of the table, 20 points clear of surprise runners-up Afghan Chaman.

Ishaq was first called by the Pakistan national team during the 2005 South Asian Football Federation Gold Cup.

[17] He subsequently played at the 2007 AFC Asian Cup qualifiers against Jordan, which was hosted in the Amman International Stadium.

[18] In 2011, Ishaq was named captain of the senior national team for the 2012 AFC Challenge Cup qualification, with Abdul Aziz as vice-captain.