Sameakki Mean Chey (Khmer: ស្រុកសាមគ្គីមានជ័យ) is a district (srok) in the south of Kampong Chhnang province, in central Cambodia.

The district shares a border with Kandal and Kampong Speu provinces to the south.

The National Railway line from Phnom Penh to Sisophon runs through the district crossing roughly from north to south.

Three smaller provincial roads cross the district from the National highway to the rail line running roughly east to west.

[3] Sameakki Mean Chey is one of two sites chosen for a 1.5 million dollar project funded by the Japan Social Development Fund through the World Bank to give state owned land to the poorest families in the district.