[3] Kambalu's work, which references Situationism and the Chewa Nyau culture of his native Malawi,[4][5] manifests in various media, from drawing, painting, installation, video to literature and performance.
[7] Kambalu held an exhibition of 24 "Holy Balls" at Chancellor College in 2000 at which he invited the visitors to “exercise and exorcise”.
[12] Kambalu's Nyau Cinema is a series of short film clips of psychogeographical performances, shared as interventions on social networking sites and as installations in galleries.
[14] His first book, an autobiographical narrative entitled The Jive Talker or How to Get a British Passport, was published by Jonathan Cape (Random House) in July 2008, and in August 2008 by Free Press (Simon & Schuster).
[18][19] On 5 July 2021, it was announced that Kambalu's artwork had been selected as the next to occupy the fourth plinth in Trafalgar Square in central London from September 2022 until 2024.