The phone was announced on 17 March 2021[3][4] at Samsung's virtual Awesome Unpacked event alongside the Galaxy A72.

It is similar to its predecessor, but features an upgraded 64 MP main camera, an increased-capacity 4500 mAh battery, and IP67 water and dust resistance.

The Galaxy A52 is powered by Qualcomm Snapdragon 720G SoC with 8 nm process, an octa-core CPU and Adreno 618 GPU.

The Galaxy A52 5G is, on the other hand, powered by Qualcomm Snapdragon 750G SoC with 8 nm process, an octa-core CPU and Adreno 619 GPU.

The device mounts a 3.5mm Audio jack and uses the top earpieces, with the bottom speaker, to deliver stereo sound.