Samuel Edward Holt (3 September 1880 – 18 April 1929) was an Irish Fianna Fáil politician.

Holt was born in Coole, County Westmeath, in 1880, the fifth child of a family of ten of David Holt, from Killina, Carbury, County Kildare, a constable in the Royal Irish Constabulary, and Agnes McColl.

[2] In 1910, Holt married Honoria Devaney, from Toomore, Boher, County Roscommon in Longford Cathedral.

[4] He was elected to Dáil Éireann as a Sinn Féin Teachta Dála (TD) for the Leitrim–Sligo constituency at the 1925 by-election on 11 March caused by the resignation of Thomas Carter of Cumann na nGaedheal.

The by-election caused by his death was held on 7 June 1929 and was won by Seán Mac Eoin of Cumann na nGaedhael.