Samuel Humphreys (23 November 1778 – 16 August 1846) was an American naval architect and shipbuilder in the early 19th century.
In 1824, Humphreys turned down a very lucrative offer from Emperor Alexander I of Russia to create a Russian navy, saying: "I do not know that I possess the merits attributed to me, but, be they great or small, I owe them all to the flag of my country."
Samuel, and his wife Letitia, had sons Andrew (1810-1883) and Joshua (1813–1873) who served in the Union Army and Confederate States Navy, respectively, in the American Civil War (1861-1865).
His other children were Jane Murray McCrabb (1813–1897), Mary Yonge (1823–1866), and William Humphreys (1828–1897).
Samuel Humphreys is buried at the Congressional Cemetery in Washington, D.C., with his sons Andrew and Joshua.