The Samuel L. Smith House is located at 5035 Woodward Avenue in Midtown Detroit, Michigan.

[4] Smith was one of the most prominent citizens of Detroit at the time, having made his fortune in lumber, shipping, mining and railroad ventures.

[4] In 1960, Wayne State University purchased the building to serve as the home for WDET and WSU's Office of the Center of Instructional Technology.

[4] The Samuel L. Smith House is a three-story, cross-gabled Queen Anne building with Romanesque and Colonial Revival elements.

A round corner tower is on one side of the facade, balanced by a Romanesque front entry arch.