[15][16] In 1956, after being convicted of breaking and entering into property in Omaha, Nebraska, Little was held in an institution for juvenile offenders.

[19] He said he then "began traveling more widely and had more run-ins with the law," being arrested in eight states for crimes that included driving under the influence, fraud, shoplifting, solicitation, armed robbery, aggravated assault, and rape.

By 1975, he had been arrested 26 times in eleven states for crimes including theft, assault, attempted rape, fraud, and attacks on government officials.

[20] In 1982, Little was arrested in Pascagoula, Mississippi, and he faced charges for the murder of 22-year-old Melinda Rose LaPree, who had gone missing in September of that year.

However, while under investigation, Little was extradited to Florida and tried for the murder of 26-year-old Patricia Ann Mount, whose body had been found in September 1982.

One month later, he was found by police in the back seat of his car with an unconscious woman, also beaten and strangled, in the same location as the attempted murder of Barros.

The prosecution presented the DNA evidence as well as testimony of witnesses who were attacked by the accused at different times throughout his criminal career.

[36] On November 19, 2018, Harrison County, Mississippi sheriff Troy Peterson said that Little had confessed to strangling 36-year-old Julia Critchfield in the Gulfport area in 1978 and dumping her body off a cliff.

[40] In December 2018, Little was indicted for strangling Linda Sue Boards, 23, to death in May 1981 in Warren County, Kentucky.

[43] The body of Rose Evans, 32, was found on August 24, 1991, in a vacant lot on East 39th St. She left her hometown of Binghamton, New York when she was 17.

[43][44] As for Peyton, an anthropologist had to create a model of what she looked like, but she remained unidentified until 1992 when Cleveland put her thumbprint in an FBI data base and got a match.

The woman murdered in 1977 or 1978 was found on March 18, 1983, in Willoughby Hills, Ohio, according to the National Missing and Unidentified Persons System.

[43] Of the two women Little murdered in Cincinnati, one was identified as Anna Stewart, 33, whose body was dumped in Grove City, Ohio.

[4] She was Black, slender, wore glasses and lived in the Over-the-Rhine neighborhood of Cincinnati with a "heavy female Hispanic".

[50] On April 22, 2022, a woman Little killed in Memphis, Tennessee, whose body was found on the Arkansas side of the Mississippi River, in 1990 was identified as 30-year-old Zena Marie Jones.

Despite the broad scope of his offending, Little was charged with and convicted of only eight murders in total as these cases had the strongest evidence of guilt:[11] Little had a long-term girlfriend, Orelia Dorsey, since deceased, who supported them both through shoplifting for years.

[96][97] Although California Department of Corrections and Rehabilitation sources indicate no cause of death, Little suffered from diabetes, heart problems, and other health conditions.

[94] Joe Berlinger read the article and thought it would be interesting for a feature-length film or documentary series and met with Lauren.

[101] The five-part television miniseries Confronting a Serial Killer, directed and produced by Berlinger,[102][103] presents her investigation and premiered on April 18, 2021, on Starz.

[104] In 2023, Lauren's book Behold the Monster: Confronting America's Most Prolific Serial Killer and Uncovering the Women Society Forgot was published by Sourcebooks.