Samuel Kisakye Sejjaaka was born on 10 January 1964 in the Mulago National Referral Hospital in Kampala, Uganda's capital and largest city.

For his O-Level and A-Level education, he studied at Kings College Budo, a mixed boarding middle and high school in Wakiso District.

He then attended the University of Strathclyde in the United Kingdom, earning a Master of Science degree in financial studies in 1990.

[4] Dr. Sejjaaka has served since 2015 as Chairman of the Board at UAP- Old Mutual Financial Services and Director since 2009 at UAP Life Insurance.

The main objective of UDBL is to promote and finance development in various sectors of the economy with particular emphasis on agriculture, industry, tourism, housing, and commerce.

The Committee is part of the governance framework that will ensure that the proceeds from oil and gas, being a non-renewable resource are wisely invested in accordance with international best practice and to the benefit of the current and future generations.

[10] In January 2022, Dr. Sejjaaka was appointed Board Chairman of Daily Monitor/Monitor Publications, the largest independent newspaper in Uganda, additionally, he was appointed as a Non-Executive Director of Nation Media Group, a media conglomerate, based in Nairobi, Kenya and whose shares are listed on the Nairobi Stock Exchange and are cross-listed on the Uganda Securities Exchange, with a controlling interest in Monitor Publications.