Samuel Thatcher (July 1, 1776 – July 18, 1872) was a member of the United States House of Representatives from Massachusetts.

He was born in Cambridge in the Province of Massachusetts Bay on July 1, 1776; was graduated from Harvard University in 1793; studied law; was admitted to the bar in 1797 and commenced practice in New Gloucester (then in Massachusetts' District of Maine); moved to Warren in 1800; member of the Massachusetts house of representatives 1801–1811; was elected as a Federalist to the Seventh Congress to fill the vacancy caused by the resignation of Silas Lee; reelected to the Eighth Congress and served from December 6, 1802, to March 3, 1805; sheriff of Lincoln County, 1814–1821; member of the Maine house of representatives in 1824; moved to Bangor, Maine, in 1860, and died there July 18, 1872; interment in Bangor's Mount Hope Cemetery.

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