Samuel Werenfels (August 4, 1720 – September 11, 1800) was a famous Swiss Baroque architect.
He was grandnephew and godson of the likewise named Swiss theologian Samuel Werenfels.
In 1743 he joined the Gesellenbruderschaft der Spinnwetternzunft in Basel and became master craftsman in 1748.
The buildings erected in Basel and the surrounding area according to Werenfels' plans, testify his stylistic continuousness to the contemporary Alsatian architecture.
Together with Johann Jacob Fechter (1717–1797) and Ulrich Büchel (1753–1792), Werenfels was one of the most distinguished architects and master builders in Basel during the 18th century.