The San Bernardino kangaroo rat (Dipodomys merriami parvus) is a species of rodent in the family Heteromyidae.

It is one of 19 recognized subspecies of Merriam's kangaroo rat (Dipodomys merriami) that are spread throughout the arid regions of the southwestern United States and Mexico.

Like Dipodomys merriami, the San Bernardino kangaroo rat has the diagnostic trait of having four toes on its hind legs.

San Bernardino kangaroo rats inhabit places with sandy loam substrates, characteristic of alluvial fans and flood plains, where they are able to dig small, simple burrows.

These alluvial scrub habitats can be classified as pioneer, intermediate, and mature, in order of decreased frequency of flooding and increased density of plants.

According to the Fish and Wildlife Service, D. m. parvus is threatened by "habitat destruction, degradation, and fragmentation by sand and gravel mining, flood control projects, urban development, vandalism, and inadequate regulatory mechanisms."

Urban development, in addition to directly destroying habitat, brings with it domesticated cats, a documented predator of the San Bernardino kangaroo rat.