San Cristóbal (Spanish pronunciation: [ˈsaŋ kɾisˈtoβal]) is a province in the southern region of Dominican Republic, located west of the capital Santo Domingo.

With approximately 642,000 inhabitants, it is the fourth most populated province in the country, only behind Santo Domingo, Santiago and the National District.

It borders the provinces Monseñor Nouel (north), Monte Plata (northeast), Santo Domingo (east), Peravia (west) and San José de Ocoa (northwest).

The industry (in San Cristóbal and the free zones of Bajos de Haina, Nigua and Villa Altagracia), small-scale agriculture (except citrus plantations in Villa Altagracia, coffee in the mountains and onions in the plains of Najayo-Palenque) and ports (in Bajos de Haina and Palenque).

The main centers are the beaches of Najayo, Palenque, El Balnearios de La Toma and the rivers Haina and Nizao.