San Francesco is a Baroque-style, Roman Catholic church located on near the railway station in the town of Canicattì, province of Agrigento, region of Sicily, Italy.
The church is attached to the ancient Convent of the Franciscans, suppressed after the annexation of Sicily to the Kingdom of Italy.
The church was begun in 1554 at the site of an early Oratory, under the patronage of Baron Giovanni Battista Bonanno.
In 1906, the Convent was converted under the patronage of Baron Francesco Lombardo, into a nursing home for the elderly, with the designs drawn up by Ernesto Basile.
The interior has a single nave once possessing 18th-century ceiling frescoes by Domenico Provenzano, but lost in the roof collapse of 1823.